Tight regulation of neural stem cell (NSC) maintenance and differentiation is crucial for the formation of the central nervous system and homeostatic neurogenesis in adults.
As part of the NeuroStemX project, we took advantage of in vivotransgenic labeling and next-generation sequencing to analyze the gene expression profiles of neural stem cells from wild type and Ski-deficient mice.
During development and maintenance of the brain, post-transcriptional regulation of gene expression by neural stem cells (NSCs) and their progeny is very important.