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Key Publications
Interferon-γ resistance and immune evasion in glioma develop via Notch-regulated...
Gliomas are aggressive brain tumors and resistant to current standard and targeted therapeutic interventions...
Parmigiani et al.
Jul 7, 2022
26 views
Oncogenic and Tumor-Suppressive Functions of NOTCH Signaling in Glioma
Paper URL: MDPI Although the role of NOTCH signaling has been extensively studied in health and disease, many questions still remain...
Parmigiani, E. Giachino, C. Taylor, V.
Oct 15, 2020
135 views
Tead transcription factors differentially regulate cortical development
Paper URL: Nature Neural stem cells (NSCs) generate neurons of the cerebral cortex with distinct morphologies and functions. How specific...
Mukhtar, T. Breda, J. Grison, A. Karimaddini, Z. Grobecker, P. Iber, D. Beisel, C. van Nimwegen E. & Taylor, V.
Mar 13, 2020
163 views
Id4 Downstream of Notch2 Maintains Neural Stem Cell Quiescence in the Adult Hippocampus
Paper URL: Science Direct Neural stem cells (NSCs) in the adult mouse hippocampal dentate gyrus (DG) are mostly quiescent, and only a few...
Zhang, R. Boareto, M. Engler, A. Louvi, A. Giachino, C. Iber, D. & Taylor, V.
Aug 6, 2019
107 views
Notch and Neurogenesis
Paper URL: Springer Neurogenesis is the process of forming neurons and is essential during vertebrate development to produce most of the...
Engler A, Zhang R, and Taylor V.
Jul 19, 2018
44 views
TDP-43 induces p53-mediated cell death of cortical progenitors and immature neurons
Paper URL: Scientific Report TAR DNA-binding protein 43 (TDP-43) is a key player in neurodegenerative diseases including frontotemporal...
Vogt MA, Ehsaei Z, Knuckles P, Higginbottom A, Helmbrecht MS, Kunath T, Eggan K, Williams LA, Shaw PJ, Wurst W, Floss T, Huber AB, Taylor V.
May 25, 2018
36 views
Untangling Cortical Complexity During Development
Paper URL: Sage Pub The cerebral cortex is composed of billions of morphologically and functionally distinct neurons. These neurons are...
Mukhtar T, Taylor V.
Mar 1, 2018
389 views
Notch2 Signaling Maintains NSC Quiescence in the Murine Ventricular-Subventricular Zone
Paper URL: Science Direct Neurogenesis continues in the ventricular-subventricular zone (V-SVZ) of the adult forebrain from quiescent...
Engler A, Rolando C, Giachino C, Saotome I, Erni A, Brien C, Zhang R, Zimber-Strobl U, Radtke F, Artavanis-Tsakonas S, Louvi A and, Taylor V
Jan 23, 2018
48 views
Boareto, M. et al. Development
Paper URL: Development Differential interactions between Notch and ID factors control neurogenesis by modulating Hes factor...
Boareto M, Iber D, and Taylor V.
Oct 1, 2017
23 views
Fedele, S. et al., Scientific Reports
Paper URL: Nature Expansion of human midbrain floor plate progenitors from induced pluripotent stem cells increases dopaminergic neuron...
Fedele S, Collo G, Behr K, Bischofberger J, Müller S, Kunath T, Christensen K, Gündner AL, Graf M, Jagasia R, Taylor V.
Jul 20, 2017
45 views
Notch: an interactive player in neurogenesis and disease
Paper URL: Springer Notch signaling is evolutionarily conserved from Drosophila to human. It plays critical roles in neural stem cell...
Zhang R, Engler A, and Taylor V.
Jun 15, 2017
14 views
Multipotency of Adult Hippocampal NSCs In Vivo Is Restricted by Drosha/NFIB
Paper URL: Science Direct Adult neural stem cells (NSCs) are defined by their inherent capacity to self-renew and give rise to neurons,...
Rolando C, Erni A, Grison A, Beattie R, Engler A, Gokhale PJ, Milo M, Wegleiter T, Jessberger S, Taylor V.
Nov 3, 2016
16 views
A Tumor Suppressor Function for Notch Signaling in Forebrain Tumor Subtypes
Paper URL: Science Direct In the brain, Notch signaling maintains normal neural stem cells, but also brain cancer stem cells, indicating...
Giachino C,Boulay JL,Ivanek R,Alvarado A,Tostado C,Lugert S,Tchorz J,Coban M,Mariani L,Bettler B,Lathia J,Frank S,Pfister S,Kool M, Taylor V
Dec 14, 2015
29 views
Neural stem cell of the hippocampus: development, physiology regulation, and dysfunction in disease
Paper URL: Science Direct The formation of the hippocampus is generated during embryonic development, but most neurons within the...
Rolando, C., Taylor V.
Oct 7, 2014
20 views
Notching up neural stem cell homogeneity in homeostasis and disease
Paper URL: Frontiers in Neuroscience Adult neural stem cells (NSCs) are perceived as a homogeneous population of cells that divide...
Giachino C, Taylor V
Feb 25, 2014
10 views
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